Find unique values in a row from 2 different columns

I have some data that looks similar to this:

Column1     Column2     Column3     Column4     Column5

GoodData    123            GoodData   ABC             GoodData

GoodData    123            GoodData   BCA             Gooddata

GoodData    456            GoodData   BCA             Gooddata

and so on....

each Columns 2 and 4 have duplicate values. I need to each unique instance where both those columns are you unique though. So if Column2 says "123" and Column4 says "ABC" for 1 row, but another row Column2 says "123" and Column4 says "BCA" I want both rows. Additionally I want both rows if Column4 is the same both rows but Column2 is different. Hopefully that makes sense. I have tried doing with sort -unique with group-object and multiple sort -unique pipes with no luck. I cant seem to figure out the trick to getting what I am looking for. Any ideas would be appreciated.

Thanks

Chris

Chris Morgan